Clinical Review for Supreme 7 Oil

The Efficacy and Safety of Supreme 7 Oil (blend of unsaturated fatty acids) and Patients with Hypertriglyceridemia (TG)


This is multi-center, prospective, randomized, double-blind, placebo-controlled on the safety and efficacy of Supreme 7 (oil blend of unsaturated fatty acids) and patients with hypertriglyceridemia (TG). The clinical trial was submitted to the Journal of Alternative Therapies and is pending publication. Revisions of this trial have not been requested by the Peer Independent Editorial Team. The purpose of the study was to test the investigational product by assessing serum lipids, low-density lipoproteins (LDL), very low-density lipoproteins (VLDL), high-density lipoproteins (HDL), chylomicrons, cytokines, and serum glucose.


Investigators (Tenet et al) examined and evaluated the efficacy of the product on the following physical signs:

  • Eruptive Palmer xanthomas (yellow creases of the palm),
  • Lipomas (benign fatty growth).
  • Hepatomegaly (enlarged liver)
  • Splenomegaly (enlarged spleen)

Materials and methods

60 subjects from two centers underwent randomization and were divided into two groups to receive either the active investigational product (Supreme 7) or a placebo with a non-active recipient. The duration of the study trial was 90 days. Patients were screened to meet the necessary inclusion and exclusion criteria for the study protocol. Thereafter, three follow-up visits were scheduled at week 4, week 8, and week 12 to ascertain the subjects' symptoms and physical findings.


Supreme 7 oil demonstrated a significant improvement in reduction of nausea, vomiting, diarrhea, loss of appetite, abdominal pain, headache, and mental disturbances. The overall improvement was 68% greater than that of the placebo group. Per marker percentages of improvement were assessed and will be available in the final publication of the trial. Moreover, investigators did not observe any adverse events from the ingestion of the investigational product.

Study Investigators

David Tenet, Ph.D., Dietetics, Private Practice, San Diego, CA. ST. Lapar County Hospital, San Diego, CA
Tony Lamam, MD, MS, Internal Medicine and Family Practice, Santa Rosa Medical Center, Santa Rosa, CA
Roger Patick, MD, Internal Medicine, Gastroenterologist. University of Montreal, Canada.
Nasser Hajjar, D, Internal Medicine, Gastroenterologist. American University of Beirut, Beirut Lebanon

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